Helicobacter pylori Detection and Antimicrobial Susceptibility Testing

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Helicobacter pylori detection and antimicrobial susceptibility testing.

The discovery of Helicobacter pylori in 1982 was the starting point of a revolution concerning the concepts and management of gastroduodenal diseases. It is now well accepted that the most common stomach disease, peptic ulcer disease, is an infectious disease, and all consensus conferences agree that the causative agent, H. pylori, must be treated with antibiotics. Furthermore, the concept emer...

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Helicobacter pylori susceptibility testing by disc diffusion.

The bacterium Helicobacter pylori is found in c. 40% of the population and is responsible for the development of duodenal disease. Triple treatment with a proton-pump inhibitor or bismuth salt plus two antibiotics is now commonplace in all patients diagnosed. As antibiotic resistance reduces treatment efficacy, it is time to consider routine susceptibility testing to guide individual patient tr...

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HELICOBACTER PYLORI Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents

Background and aim: The role of Helicobacter pylori and aspirin in peptic ulcer formation and recurrence remains an important clinical topic. The interaction between aspirin and H pylori in vitro is also not clear. We investigated the effect of aspirin on the growth of H pylori and on the susceptibility of H pylori to antimicrobials. Methods: Time killing studies of H pylori were performed with...

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No standardized method of susceptibility testing for Helicobacter pylori is currently available, so before a large agar dilution study comprising 230 H. pylori strains belonging to more than 80 genetically different groups was initiated, we performed a relatively small preliminary study to determine the influences of medium, inoculum density, and incubation time. Seven media were investigated a...

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ژورنال

عنوان ژورنال: Clinical Microbiology Reviews

سال: 2007

ISSN: 0893-8512,1098-6618

DOI: 10.1128/cmr.00033-06